Pathophysiology

Duration of viral shedding
Question:  How long do people shed coronavirus? Contributors: Danielle Urman, Andrew Chang Summary document: Virus Shedding Duration Lit search:...
Thu, Jul 16, 2020 at 3:29 PM
Vaccine cross-resistance (including BCG)
Are there any studies/documentation about potential cross-resistance imparting protection against coronavirus infection? For example, are kids less suscepti...
Thu, Jul 16, 2020 at 3:02 PM
Protective immunity after infection
What do we know about protective immunity? Can titers be used to help health care workers back to work? Timing/duration? https://relief.unboundmedicine....
Thu, Jul 16, 2020 at 3:03 PM
Concurrent PE and COVID
Are there any reports of PE in COVID-presenting patients (since both would present with hypoxia, tachycardia, SOB, elevated d-dimer)? https://relief.unb...
Thu, Jul 16, 2020 at 3:05 PM
Dose dependent severity
What data do we have from COVID to support "dose dependent" severity? Are healthcare workers or caregivers to COVID19 pts disproportionately getti...
Thu, Jul 16, 2020 at 3:08 PM
Neurologic manifestations
What are the neurologic manifestations of COVID-19?  There are reports of encephalitis from the cytokine storm. What are the other documented symptoms?  Any...
Thu, Jul 16, 2020 at 3:08 PM
Microthrombi as cause of hypoxemia / use of tPA
What evidence do we have for microthrombi as cause of poor perfusion / difficult oxygenation in severe COVID-19?  What evidence for use of tPA? https://rel...
Thu, Jul 16, 2020 at 3:09 PM
Smoking and COVID-19
https://relief.unboundmedicine.com/relief/view/CoRespond-Emerging-Topics/2425035/all/Smoking_and_COVID_19_severity
Thu, Jul 16, 2020 at 3:09 PM
Oxygenation and potential mechanisms of hypoxemia from COVID
Any other potential mechanisms for low tissue oxygenation after ventilation support? If true, what would be the proposed treatment/management? https://reli...
Thu, Jul 16, 2020 at 3:10 PM
Long term sequelae
https://relief.unboundmedicine.com/relief/view/CoRespond-Emerging-Topics/2425053/all/Long_Term_Sequelae_of_COVID_19
Tue, Jul 21, 2020 at 12:03 PM